Guidelines regarding constitution / reconstitution of IAEC 48th Meeting of CPCSEA was held on 21st August, under the Chairmanship of Shri Hem. PDF | The effect of implementation of guidelines of the Committee for the Purpose of Control and The results showed that the implementation of CPCSEA guidelines in pharmacy institution . Mar ; J Indian Assoc Pediatr Surg. PDF | On Dec 29, , Pandey Govind and others published Guidelines of CPCSEA for conducting the experiment on animals.

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Animal testing is bad science.

Regulations for use of animals for experiments and research The first animal protection law to regulate animal testing was in enacted in in the British parliament, followed by the Cruelty to Animals Act Cell culture is a promising alternative to animal use. Examples include, improved experimental design and statistical analysis, modern imaging techniques, avoiding repetitions of tests to prove established hypothesis and sharing data and resources[ 2425 ].

People for the ethical treatment of animals. Refinement, reduction, and replacement of animal use for regulatory testing: BBC news; [Last accessed on May 30]. On the other side of the coin are scientists who advocate the relevant and judicious use of animals in research so that new discoveries can continue. Substitute of animals in drug research: Medical council of India, New Delhi, amendment notification of 8 July to the Minimal standard requirements for medical colleges with admissions annually, regulations.

Animal use in pharmacology education and research: The changing scenario

The various alternatives used are mannequins, videos, observational and field studies, materials from slaughter house and fisheries, supervised clinical experience etc. It refers to decreased invasiveness, improved instrumentation, improved control of pain which minimize actual or potential pain, suffering and distress.

Badyal and Chetna Desai 1. The use of animals in research and education dates back to the period when humans started to look for ways to prevent and cure ailments. University of Edinburgh, UK. Enquiries through email will be prefered. In India, few software programs which replace animal experiments are available in pharmacology teaching since Annual report animal usage by cpcses year, United States department of agriculture, animal and plant inspection service.


Alternatives or substitutes to animal experimentation is defined as anything from absolute to partial replacement of live animals in biomedical research and experimentation.

Animal use in pharmacology education and research: The changing scenario

It has been seen that selected group of fungi have the ability to metabolize a wide variety of drugs. Many in vitro techniques have evolved, but the concept is new and awaits validation and standardization. It seems likely that these alternative methods and models will eventually replace intact animal models in pharmacology education, either partially or completely.

These are mechanistic models that aim to predict sensitization from mechanistic knowledge and empirical models that are aimed at predicting from a statistical perspective. Similarly, fruit flies can be useful to identify novel virulence factors or guidelinrs active compounds.

The prevention of cruelty to animals act, as amended by Central Act 26 of Vision guivelines, Medical Council of India. We evaluated these software programs and found that the alternatives are implementable and decrease the cost and time spent on animal experiments.

Computer simulation models are implementable as replacements for animal experiments. Methods which minimize animal use and enable researchers to obtain comparable levels of information from fewer animals or to obtain more information from the same number of animals.

Statistics of scientific procedures on living animals. For example, within the European Union, the local lymph node cpcssea LLNA is the preferred method for assessing skin sensitization potential, whereas cpcswa pig assays are still preferred in other regions of the world e. Similarly, the response of faculty in India to training on alternatives was very encouraging.


Postgraduate teaching to demonstrate the effects of various drugs, to determine the nature of an unknown drug for bioassay, screening methods and to learn skills e. Is the animal the best experimental system for cpcsra hypothesis to be tested? These laboratory animals are obtained from various sources in different countries.

Another example is the use of fungi for studies of the metabolism of drugs. Confusion, contradiction, and controversy. Cosmetic testing on animals is particularly controversial and involves general toxicity, eye and skin irritancy, phototoxicity and mutagenicity.

In view of this, non-animal alternatives are being developed wherever necessary. Alternatives to animals in education, research and risk assessment: InJennifer Graham from California sued her high school for insisting that dissection was the only method they recognized for learning anatomy.

Indian National science academy. Animal experiments, for long, have been an integral part of the pharmacology education at medical colleges in India. The institution’s veterinarian or institutional animal care or institute animal ethics committee IAECfor care and use of animals advise the researchers for the use of animals in their respective research projects.

Drugs, an important tool in healthcare, are introduced in therapeutics after experimental evaluation. Examples include, established animal cell lines, animal cells, tissues and organs collected from animals sacrificed by a humane technique, abattoir material, invertebrates, such as Drosophila and nematode worms, larval forms of amphibians and fish until the stage where they become capable of independent feeding and bacteria, fungi etc[ 2430 ].

Development of alternatives to animal experiments in teaching seems less tedious.